李蕾蕾

博士，讲师
Email：02268@aynu.edu.cn




      研究方向为阐明蛋白翻译后修饰（泛素化，磷酸化）在恶性肿瘤发生发展中的作用及调控机制，探寻癌症治疗新靶点，开发新的抗肿瘤策略；同时，从事临床抗肿瘤药物耐药的分子机制研究。承担课程：微生物学、生物化学等。
2020-2025 山东大学   药学院 药理学专业   医学博士
2017-2020 郑州大学   药学院 药学专业     药学硕士
2013-2017 新乡医学院 药学院 药物制剂专业 理学学士
2025.09-至今 化学化工学院 讲师
生物化学

1. Leilei Li, Tao Zhang*. USP1 promotes pancreatic cancer progression and autophagy by deubiquitinating ATG14. Journal of Biological Chemistry, 2025.
2.Leilei Li; Xinyu Gu; Tao Zhang; Deubiquitinases in DNA damage repair: Implication and mechanism in cancer, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2025
3. Chengchun Zhu, Leilei Li, Tao Zhang*, Zhiyi Yu*. Optimization of SHP2 allosteric inhibitors with novel tail heterocycles and their potential as antitumor therapeutics. European Journal of Medicinal Chemistry, 2024.
4. Jinzhu Zhao, Leilei Li, Cong Wang*. Luteolin attenuates cancer cell stemness in PTX-resistant oesophageal cancer cells through mediating SOX2 protein stability. Pharmacological Research, 2021.
5. Cong Wang, Leilei Li, Xiufang Shi*. Chalcone-modified estradiol analogs as antitumour agents that inhibit tumour angiogenesis and epithelial to mesenchymal transition. European Journal of Medicinal Chemistry,2019.
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