刘林,博士,教授,河南省学术技术带头人,河南省高校科技创新人才,河南省高等学校青年骨干教师,安阳师范学院国际合作交流中心主任。2011年7月获中南大学应用化学专业博士学位,博士期间(2009.6~2010.12)在美国加州州立大学洛杉矶分校进行了18个月的访学工作;2011年9月进入安阳师范学院任教。主讲《生物化学》、《微生物学与免疫学》、《分析化学实验》、《科技论文写作》等理论实验课程。主要从事重大疾病早期诊断与药物开发等方面的研究工作,目前已发表SCI论文110余篇,其中,以第一作者、通讯作者在J. Am. Chem. Soc., Green Chem., Chem. Commun., Biosens. Bioelectron., ACS Appl. Mater. Interfaces, Electrochem. Commun., Sensor. Actual. B:Chem., Electrochem. Acta, Analyst等国际知名期刊杂志上发表SCI论文70余篇,以第一作者发表在 J. Am. Chem. Soc. (2011, 133, 12229–12237)上的研究成果被美国化学会Chemical & Engineering News(2011, 89(31): 36 ISSN 0009-2347)选作专题报道,以通讯作者发表在Green Chem.上的论文被选作杂志封面。目前已主持完成国家自然科学基金项目1项,河南省科技厅项目1项,河南省教育厅重点项目1项,河南省高校科技创新人才项目1项,作为第二完成人完成国家自然科学基金项目4项。获河南省科技进步奖贰等奖2项:用于早期诊断与药物开发的电化学传感技术(第一完成人)和绿色化学法制备、改性纳米材料基础研究(第六完成人)。申请国家发明专利9项,已授权6项。出版专著1部。
近五年发表的代表性论文
1. Xia, Ning; Deng, Dehua; Yang, Suling; Hao, Yuanqiang; Wang, Luyan; Liu, Yuwei;An, Cuixia; Han, Qiuyang; Liu, Lin*. Electrochemical immunosensors with protease as the signal label for the generation of peptide-Cu(II) complexes as the electrocatalysts toward water oxidation, 2019年, Sensors and Actuators B: Chemical, 291: 113-119
2. Dehua, Deng; Yuanqiang, Hao; Suling, Yang; Qiuyang, Han; Lin, Liu*; Yanrong, Xiang; Fanbin, Tu; Ning, Xia. A signal-on electrochemical biosensor for evaluation of caspase-3 activity and cell apoptosis by the generation of molecular electrocatalysts on graphene electrode surface for water oxidation, 2019年, Sensors and Actuators B: Chemical, 286: 415-42
3. Lin, Liu*; Dehua, Deng; Yiru, Wang; Kewei, Song; Ziling, Shang; Qiao, Wang; Ning, Xia; Bing, Zhang*. A colorimetric strategy for assay of protease activity based on gold nanoparticle growth controlled by ascorbic acid and Cu(II)-coordinated peptide, 2018年, Sensors and Actuators B: Chemical, 266: 246-254
4. Dehua, Deng; Lin, Liu*; Yingping, Bu; Xiuhua, Liu; Xuezhen, Wang; Bing, Zhang*. Electrochemical sensing devices using ATCUN-Cu(II) complexes as electrocatalysts for water oxidation, 2018年, Sensors and Actuators B, 269: 189–194
5. Kai, Sun; Xin, Wang; Fangfang, Fu; Chong, Zhang; Yao, Chen; Lin Liu*. Metal-free Selenosulfonylation of Alkynes: Rapid Access to β-(Seleno)vinyl Sulfones via a Cationic-species-induced Pathway, 2017年, Green Chem, 19: 1490-1493.
6. Leilei, Liu; Yong, Chang; Ning, Xia; Peizhen, Peng; Liping, Zhang; Mengsha, Jiang; Jiebin, Zhang; Lin, Liu*. Simple, sensitive and label-free electrochemical detection of microRNAs based on the in situ formation of silver nanoparticles aggregates for signal amplification, 2017年, Biosensors and Bioelectronics, 94: 235-242
7. Kai, Sun; Ning, Xia; Lijuan, Zhao; Ke, Liu; Wenjing, Hou; Lin Liu*. Aptasensors for the Selective Detection of Alpha-synuclein Oligomer by Colorimetry, Surface Plasmon Resonance and Electrochemical Impedance Spectroscopy, 2017年, Sensors and Actuators B: Chemical, 245: 87-94
8. Lin, Liu*; Yong, Chang; Jie, Yu; Mengsha, Jiang; Ning, Xia.Two-in-one polydopamine nanospheres for fluorescent determination of beta-amyloid oligomers and inhibition of beta-amyloid aggregation, 2017年,Sensors and Actuators B: Chemical, 251: 359-365
9. Lin, Liu*; Cheng, Cheng; Yong, Chang; Huiyun, Ma; Yuanqiang, Hao. Two sensitive electrochemical strategies for the detection of protein kinase activity based on the 4-mercaptophenylboronic acid-induced in situ assembly of silver nanoparticles, 2017年, Sensors and Actuators B: Chemical, 248:178-186
10. LeiLei, Liu; Jing, Chen; CaiXia, Yu; WenXing, Lv; HuiYing, Yu; XiaoQing, Cui; Lin, Liu*. A novel Ag(I)-calix[4]arene coordination polymer for the sensitive detection and efficient photodegradation of nitrobenzene in aqueous solution, 2017年,Dalton Trans, 46: 178-185
11. Xia, Ning; Liu, Lin*; Chang, Yong; Hao, Yuanqiang; Wang, Xiaojin. 4-Mercaptophenylboronic acid-induced in situ formation of silver nanoparticle aggregates as labels on an electrode surface, 2017年, Electrochemistry Communications, 74: 28-32
12. Xia, Ning; Wang, Xin; Yu, Jie;Wu, Yangyang; Cheng, Shuchao;Xing, Yun; Liu,Lin*. Design of electrochemical biosensors with peptide probes as the receptors of targets and the inducers of gold nanoparticles assembly on electrode surface, 2017年, Sensors and Actuators B: Chemical, 239: 834-840
13. Ning, Xia; Zhihua, Chen; Yadong, Liu; Huizhu, Ren; Lin, Liu*. Peptide aptamer-based biosensor for the detection of human chorionic gonadotropin by converting silver nanoparticles-based colorimetric assay into sensitive electrochemical analysis, 2017年, Sensors and Actuators B: Chemical, 243: 784-791
14. Xia, Ning; Wang, Xin; Zhou, Binbin; Wu, Yangyang; Mao, Wenhui; Liu, Lin*. Electrochemical detection of amyloid-beta oligomers based on the signal amplification of a network of silver nanoparticles, 2016年, ACS Applied Materials & Interfaces, 8: 19303-19311
15. Lin, Liu*; Ning, Xia; Jie, Yu. A graphene oxide-based fluorescent scheme for the determination of the activity of the beta-site amyloid precursor protein (BACE1) and its inhibitors, 2016年, Microchimica Acta, 183: 265–271
16. Xia, Ning; Zhou, Binbin; Huang, Nanbing; Jiang, Mengsha; Zhang, Jiebing; Liu, Lin*. Visual and fluorescent assays for selective detection of beta-amyloid oligomers based on the inner filter effect of gold nanoparticles on the fluorescence of CdTe quantum dots, 2016年, Biosensors and Bioelectronics, 85: 625-632
17. Xia, Ning; Peng, Peizhen; Wang, Shasha; Du, Jiaying; Zhu, Gaihong; Du, Weimin; Liu, Lin*. A signal-on electrochemical strategy for protease detection based on the formation of ATCUN-Cu(II), 2016年, Sensors and Actuators B: Chemical , 232: 557-563
18. Xia, Ning; Zhang, Youjuan ; Guan, Pengpeng; Hao, Yuanqiang; Liu, Lin*. A simple and label-free electrochemical method for detection of beta-site amyloid precursor protein cleaving enzyme and screening of its inhibitor, 2015年, Sensors and Actuators B: Chemical , 213: 111-115
19. Xia, Ning; Zhang, Youjuan; Wei, Xin; Huang, Yaping; Liu, Lin*. An electrochemical microRNAs biosensor with the signal amplification of alkaline phosphatase and electrochemical–chemical chemical redox cycling, 2015年, Analytica Chimica Acta, 878: 95-101
20. Lin, Liu*; Yanping, Gao; Huiping, Liu; Ning, Xia. An ultrasensitive electrochemical miRNAs sensor based on miRNAs-initiated cleavage of DNA by duplex-specific nuclease and signal amplification of enzyme plus redox cycling reaction, 2015年, Sensors and Actuators B: Chemical, 208: 137-142
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